Search results for " Phenotype"

showing 10 items of 219 documents

C 3 –C 4 intermediates may be of hybrid origin – a reminder

2017

Summary The currently favoured model of the evolution of C4 photosynthesis relies heavily on the interpretation of the broad phenotypic range of naturally growing C3–C4 intermediates as proxies for evolutionary intermediate steps. On the other hand, C3–C4 intermediates had earlier been interpreted as hybrids or hybrid derivates. By first comparing experimentally generated with naturally growing C3–C4 intermediates, and second summarising either direct or circumstantial evidence for hybridisation in lineages comprising C3, C4 and C3–C4 intermediates, we conclude that a possible hybrid origin of C3–C4 intermediates deserves careful examination. While we acknowledge that the current model of C…

0106 biological sciences0301 basic medicineGeneticsPhysiologyIntermediate phenotypePlant ScienceBiology01 natural sciences03 medical and health sciencesMoricandia arvensis030104 developmental biologyPhylogenetics010606 plant biology & botanyHybridNew Phytologist
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Kindness to the final host and vice versa: A trend for parasites providing easy prey?

2019

Traditionally the “extended phenotype” concept refers to parasites that manipulate host phenotype to increase parasite fitness. This includes parasites that render intermediate hosts more susceptible to predation by final hosts. We explore here the proposition that an evolutionary driver in such cases is the energetic benefit to the final host, in addition to increased parasite fitness. We will review some well-established host-manipulation models, where such a scenario seems likely. One example is provided by the protozoan Toxoplasma gondii, which conspicuously impairs predator avoidance in rodents. Pathologies in humans that acquire T. gondii are known, but infection in adult feline defin…

0106 biological sciences0301 basic medicinelcsh:EvolutionZoology010603 evolutionary biology01 natural sciencesPredation03 medical and health scienceslcsh:QH540-549.5lcsh:QH359-425Parasite hostingcost-benefitEcology Evolution Behavior and SystematicsCoevolutionTrophic levelEcologybiologyHost (biology)Transmission (medicine)extended phenotypeToxoplasma gondiibiology.organism_classificationimmunityPeer review030104 developmental biologyarms racecoevolutionparasite manipulationlcsh:Ecology
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The genome sequencing of an albino Western lowland gorilla reveals inbreeding in the wild

2013

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.-- et al.

0106 biological sciencesConservation geneticsMalegenotype phenotype correlationGorillaComputingMilieux_LEGALASPECTSOFCOMPUTINGarginineGenoma humà01 natural sciencesOculocutaneous albinism type 4single nucleotide polymorphismAlbinismegenetic variabilityGorillaInbreedinggenetic conservationGenetics0303 health sciencesGenomebiologyarticlecopy number variationHigh-Throughput Nucleotide SequencingSLC45A2 geneGenomicszygosityOculocutaneous albinismFloquet de neu (Goril·la)AlbinismFemaleBiotechnologyamino acid substitutionResearch ArticleSLC45A2Gorilla gorilla gorillaHeterozygoteAlbinismMolecular Sequence Datacomparative genomic hybridizationgene sequenceConservation010603 evolutionary biology03 medical and health sciencesWestern lowland gorillabiology.animalmedicineGeneticsheterozygosityAnimalsAmino Acid Sequencegene030304 developmental biologygene identificationWhole genome sequencingnonhumanGorilla gorillaMembrane Transport ProteinsSequence Analysis DNA15. Life on landbiology.organism_classificationmedicine.diseaseGenòmicaData_GENERALMutationbiology.proteinGenèticaoculocutaneous albinismglycineMicrosatellite RepeatsBMC Genomics
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The roles of temperature, nest predators and information parasites for geographical variation in egg covering behaviour of tits (Paridae)

2020

Abstract Aim: Nest building is widespread among animals. Nests may provide receptacles for eggs, developing offspring and the parents, and protect them from adverse environmental conditions. Nests may also indicate the quality of the territory and its owner and can be considered as an extended phenotype of its builder(s). Nests may, thus, function as a sexual and social signal. Here, we examined ecological and abiotic factors—temperature, nest predation and interspecific information utilization—shaping geographical variation in a specific nest structure—hair and feather cover of eggs—and its function as an extended phenotype before incubation in great (Parus major) and blue tits (Cyanistes …

0106 biological sciencesEconomicsBiology010603 evolutionary biology01 natural sciencesPredation03 medical and health sciencesCyanistes caeruleusNestbird nestParus majorBiologyEcology Evolution Behavior and SystematicsComputingMilieux_MISCELLANEOUS030304 developmental biology0303 health sciencesbreeding successEcologyOcellsEcologyextended phenotype15. Life on landBird nestChemistryVariation (linguistics)[SDE]Environmental Sciencesnest structure
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Modularity as a source of new morphological variation in the mandible of hybrid mice.

2012

Abstract Background Hybridization is often seen as a process dampening phenotypic differences accumulated between diverging evolutionary units. For a complex trait comprising several relatively independent modules, hybridization may however simply generate new phenotypes, by combining into a new mosaic modules inherited from each parental groups and parts intermediate with respect to the parental groups. We tested this hypothesis by studying mandible size and shape in a set of first and second generation hybrids resulting from inbred wild-derived laboratory strains documenting two subspecies of house mice, Musmusculus domesticus and Musmusculus musculus. Phenotypic variation of the mandible…

0106 biological sciencesEvolutionMandible[SDV.BID]Life Sciences [q-bio]/BiodiversityModels Biological010603 evolutionary biology01 natural sciencesHouse mouse[ SDV.BDD.MOR ] Life Sciences [q-bio]/Development Biology/MorphogenesisMandible (arthropod mouthpart)Mice03 medical and health sciencesQH359-425AnimalsBody SizeMus musculusMandible shapeTransgressive phenotypesHybridizationEcology Evolution Behavior and Systematics030304 developmental biologyHybridGenetics[ SDV.BID ] Life Sciences [q-bio]/Biodiversity0303 health sciencesModularity (networks)Geometric morphometricsbiology[SDV.BDD.MOR]Life Sciences [q-bio]/Development Biology/Morphogenesisbiology.organism_classification<it>Mus musculus</it>PhenotypeHouse mouseEvolutionary biologyTraitHybridization GeneticHouse miceTransgressiveResearch Article
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Reverse-engineering the Arabidopsis thaliana transcriptional network under changing environmental conditions

2009

46 pages, 4 tables, 6 figures, 3 additinoal files.

0106 biological sciencesMESH: Genome PlantArabidopsis thalianaGene regulatory networkArabidopsis01 natural sciencesTranscriptomeGene Expression Regulation PlantArabidopsisMESH: Gene Expression Regulation DevelopmentalCluster AnalysisGene Regulatory NetworksMESH: ArabidopsisMESH: EcosystemMESH: Models GeneticOligonucleotide Array Sequence AnalysisMESH: Gene Regulatory NetworksGenetics0303 health sciencesMESH: Stress MechanicalbiologyMESH: Genomicsfood and beveragesGene Expression Regulation DevelopmentalGenomicsPhenotypeAlgorithmsGenome PlantMESH: MutationSystems biologyGenomicsMESH: AlgorithmsComputational biologyMESH: Arabidopsis ProteinsMESH: Phenotype03 medical and health sciencesMESH: Gene Expression Profiling[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular BiologyMESH: Gene Expression Regulation PlantEcosystem030304 developmental biologyModels GeneticMicroarray analysis techniquesArabidopsis ProteinsGene Expression ProfilingResearchfungiRobustness (evolution)biology.organism_classificationMESH: Cluster AnalysisGene expression profilingMutationMESH: Oligonucleotide Array Sequence AnalysisStress Mechanical010606 plant biology & botany
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Paternal age negatively affects sperm production of the progeny.

2021

International audience; Parental age has profound consequences for offspring’s phenotype. However, whether patrilineal age affects offspring sperm production remains unknown, despite the importance of sperm production for male reproductive success in species facing post-copulatory sexual selection. Using a longitudinal dataset on ejaculate attributes of the houbara bustard, we showed that offspring sired by old fathers had different age-dependent trajectories of sperm production compared to offspring sired by young fathers. Specifically, they produced less sperm (−48%) in their first year of life, and 14% less during their lifetime. Paternal age had the strongest effect, with weak evidence …

0106 biological sciencesMaleAgingOffspring010603 evolutionary biology01 natural sciencesPaternal Age[SDV.BDLR.RS]Life Sciences [q-bio]/Reproductive Biology/Sexual reproductionejaculate qualityBirdsReproductive senescencereproductive senescence[SDV.BA.ZV]Life Sciences [q-bio]/Animal biology/Vertebrate ZoologyAnimalsBustardEcology Evolution Behavior and Systematicsreproductive and urinary physiologybiologyReproductive successEcology010604 marine biology & hydrobiologyReproductionbiology.organism_classificationSpermSpermatozoamale gametesAgeingSexual selectionpost copulatory sexual selectionSpermatogenesisDemographyoffspring phenotypeEcology lettersReferences
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When less means more: evolutionary and developmental hypotheses in rodent molars.

2012

10 pages; International audience; Tooth number in rodents is an example of reduction in evolution. All rodents have a toothless diastema lacking canine and most premolars present in most other mammals. Whereas some rodent lineages retained one premolar (p4), many others lost it during evolution. Recently, an 'inhibitory cascade' developmental model (IC) has been used to predict how the first molar (m1) influences the number and relative sizes of the following distal molars (m2 and m3). The model does not, however, consider the presence of premolars, and here we examine whether the premolar could influence and constrain molar proportions during development and evolution. By investigating a l…

0106 biological sciencesMolarRodentmolar proportionsRodentiapremolarBiologyMacroevolutionModels Biological010603 evolutionary biology01 natural sciencesMandibular first molar03 medical and health sciencesstomatognathic systembiology.animalevolutionPremolarmedicineAnimalsdevelopmentEcology Evolution Behavior and Systematics[ SDU.STU.PG ] Sciences of the Universe [physics]/Earth Sciences/Paleontology030304 developmental biology0303 health sciencesmacroevolutionDentition[SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]Anatomyinhibitory cascadeBiological EvolutionMolar[ SDV.BID.EVO ] Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]medicine.anatomical_structureEvolutionary biologyrodentsDiastemaLinear ModelsBasal phenotype[SDU.STU.PG]Sciences of the Universe [physics]/Earth Sciences/Paleontology
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Arabidopsis thaliana nicotianamine synthase 4 is required for proper response to iron deficiency and to cadmium exposure.

2013

International audience; The nicotianamine synthase (NAS) enzymes catalyze the formation of nicotianamine (NA), a non-proteinogenic amino acid involved in iron homeostasis. We undertook the functional characterization of AtNAS4, the fourth member of the Arabidopsis thaliana NAS gene family. A mutant carrying a T-DNA insertion in AtNAS4 (atnas4), as well as lines overexpressing AtNAS4 both in the atnas4 and the wild-type genetic backgrounds, were used to decipher the role of AtNAS4 in NA synthesis, iron homeostasis and the plant response to iron deficiency or cadmium supply. We showed that AtNAS4 is an important source for NA. Whereas atnas4 had normal growth in iron-sufficient medium, it dis…

0106 biological sciences[ SDV.BV ] Life Sciences [q-bio]/Vegetal BiologyMESH : Azetidinecarboxylic AcidFMN ReductaseArabidopsis thalianaMutantArabidopsisGene ExpressionPlant Science01 natural sciencesMESH : Cation Transport ProteinsMESH : IronMESH : Arabidopsis ProteinsNicotianamine synthaseMESH : Plants Genetically Modifiedchemistry.chemical_compoundMESH : ArabidopsisGene Expression Regulation PlantGene expressionMESH: Genes PlantArabidopsis thalianaMESH : DNA BacterialHomeostasisMESH: ArabidopsisNicotianamineMESH: Stress PhysiologicalCation Transport ProteinsMESH : Adaptation PhysiologicalMESH : Cadmium2. Zero hungerchemistry.chemical_classification0303 health sciencesCadmiumMESH: IronbiologyGeneral MedicineIron DeficienciesPlants Genetically ModifiedAdaptation PhysiologicalMESH: Azetidinecarboxylic AcidMESH : PhenotypePhenotypeBiochemistryMESH: HomeostasisMESH : HomeostasisMESH : MutationAzetidinecarboxylic AcidCadmiumDNA BacterialMESH: Gene ExpressionMESH: MutationIronMESH: Cadmiumchemistry.chemical_elementMESH: FerritinsMESH: Arabidopsis ProteinsMESH: Alkyl and Aryl TransferasesGenes PlantMESH: PhenotypeNicotianamine synthase03 medical and health sciencesMESH: Cation Transport ProteinsStress PhysiologicalIron homeostasisGenetics[SDV.BV]Life Sciences [q-bio]/Vegetal BiologyIron deficiency (plant disorder)MESH: Gene Expression Regulation PlantMESH : Genes PlantMESH : Alkyl and Aryl TransferasesMESH : Stress Physiological030304 developmental biologyMESH : FMN ReductaseAlkyl and Aryl TransferasesArabidopsis ProteinsIron deficiencyNitric oxideNicotianaminebiology.organism_classificationMESH: Adaptation PhysiologicalMESH: DNA BacterialMESH : Gene ExpressionEnzymechemistryMESH: FMN ReductaseMESH: Plants Genetically ModifiedFerritinsMutationbiology.proteinMESH : FerritinsAgronomy and Crop ScienceMESH : Gene Expression Regulation Plant010606 plant biology & botany
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Spectrum of mutations in Italian patients with familial hypercholesterolemia: New results from the LIPIGEN study

2017

Abstract Background Familial hypercholesterolemia (FH) is an autosomal dominant disease characterized by elevated plasma levels of LDL-cholesterol that confers an increased risk of premature atherosclerotic cardiovascular disease. Early identification and treatment of FH patients can improve prognosis and reduce the burden of cardiovascular mortality. Aim of this study was to perform the mutational analysis of FH patients identified through a collaboration of 20 Lipid Clinics in Italy (LIPIGEN Study). Methods We recruited 1592 individuals with a clinical diagnosis of definite or probable FH according to the Dutch Lipid Clinic Network criteria. We performed a parallel sequencing of the major…

0301 basic medicineApolipoprotein ECandidate geneSettore MED/09 - Medicina InternaDatabases FactualApolipoprotein BDNA Mutational AnalysisFamilial hypercholesterolemia030204 cardiovascular system & hematologyCompound heterozygosityPCSK90302 clinical medicineRisk FactorsReceptorsGeneticsHomozygoteAutosomal dominant traitPathogenic variantsGeneral MedicinePrognosisAPOB; Familial hypercholesterolemia; LDLR; PCSK9; Pathogenic variantsCholesterolPhenotypeItalyAutosomal Recessive HypercholesterolemiaApolipoprotein B-100lipids (amino acids peptides and proteins)Proprotein Convertase 9APOBCardiology and Cardiovascular MedicinePreliminary DataGenetic MarkersFamilial hypercholesterolemiaLDLRPCSK9APOBPathogenic variantsHeterozygoteFamilial hypercholesterolemiaBiologyPathogenic variantLDLHyperlipoproteinemia Type II03 medical and health sciencesDatabasesmedicineInternal MedicineHumansAPOB; Familial hypercholesterolemia; LDLR; Pathogenic variants; PCSK9; Internal Medicine; Cardiology and Cardiovascular MedicineGenetic Predisposition to DiseaseFactualPCSK9Settore MED/13 - ENDOCRINOLOGIAAPOB; Familial hypercholesterolemia; LDLR; Pathogenic variants; PCSK9; Cardiology and Cardiovascular Medicine; Internal Medicinemedicine.diseaseAtherosclerosis030104 developmental biologyLDLRReceptors LDLMutationbiology.proteinAPOB; Familial hypercholesterolemia; LDLR; Pathogenic variants; PCSK9; Apolipoprotein B-100; Atherosclerosis; Cholesterol; DNA Mutational Analysis; Databases Factual; Genetic Markers; Genetic Predisposition to Disease; Heterozygote; Homozygote; Humans; Hyperlipoproteinemia Type II; Italy; Phenotype; Preliminary Data; Prognosis; Proprotein Convertase 9; Receptors LDL; Risk Factors; Mutation; Internal Medicine; Cardiology and Cardiovascular Medicine
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